Use of a Novel Real-Time PCR Assay To Detect Oral Polio Vaccine Shedding and Reversion in Stool and Sewage Samples after a Mexican National Immunization Day

During replication, oral polio vaccine (OPV) can revert to neurovirulence and cause paralytic poliomyelitis. In individual vaccinees, it can acquire specific revertant point mutations, leading to vaccine-associated paralytic poliomyelitis (VAPP). With longer replication, OPV can mutate into vaccine-...

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Detalles Bibliográficos
Main Authors: Troy, Stephanie B., Ferreyra-Reyes, Leticia, Huang, ChunHong, Mahmud, Nadim, Lee, Yu-Jin, Canizales-Quintero, Sergio, Flaster, Harry, Báez-Saldaña, Renata, García-García, Lourdes, Maldonado, Yvonne
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2011
Assuntos:
Virology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3122635/
https://ncbi.nlm.nih.gov/pubmed/21411577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.02524-10
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