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Molecular design of a eukaryotic messenger RNA and its chemical synthesis.

A designed mRNA consisting of 42 ribonucleotides having the cap structure was synthesized. The capped leader sequence of the brome mosaic virus (BMV) mRNA 4, m7G5'pppGUAUUAAUA (F-1), was synthesized by the phosphotriester method and followed by the capping reaction. A 32-mer consisting of an in...

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Autores principales: Iwase, R, Maeda, M, Fujiwara, T, Sekine, M, Hata, T, Miura, K
Formato: Artigo
Lenguaje:Inglês
Publicado: 1992
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC312250/
https://ncbi.nlm.nih.gov/pubmed/1374557
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