Random mutagenesis of Schizosaccharomyces pombe SRP RNA: lethal and conditional lesions cluster in presumptive protein binding sites.

Signal recognition particle (SRP), a ribonucleoprotein composed of six polypeptides and one RNA subunit, serves as an adaptor between the cytoplasmic protein synthetic machinery and the translocation apparatus of the endoplasmic reticulum. To begin constructing a functional map of the 7SL RNA compon...

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Bibliographic Details
Main Authors: Liao, X, Selinger, D, Althoff, S, Chiang, A, Hamilton, D, Ma, M, Wise, J A
Format: Artigo
Language:Inglês
Published: 1992
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC312245/
https://ncbi.nlm.nih.gov/pubmed/1315954
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