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Analysis of the rat ribosomal DNA promoter: characterization of linker-scanning mutants and of the binding of UBF.

To investigate the mechanism of transcription of the rat ribosomal DNA (rDNA) promoter, a series of 23 linker-scanning mutants were constructed and assayed in transfected CHO cells and with cell-free extracts. With minor variation, the results of the in vitro and in vivo assays paralleled one anothe...

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Detalhes bibliográficos
Main Authors: Xie, W, O'Mahony, D J, Smith, S D, Lowe, D, Rothblum, L I
Formato: Artigo
Idioma:Inglês
Publicado em: 1992
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC312242/
https://ncbi.nlm.nih.gov/pubmed/1579451
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