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Fungicidal Monoclonal Antibody C7 Interferes with Iron Acquisition in Candida albicans †

We have developed a monoclonal antibody (MAb), C7, that reacts with the Als3p and enolase present in the Candida albicans cell wall and exerts three anti-Candida activities: candidacidal activity and inhibition of both adhesion and filamentation. To investigate the mode of action of MAb C7 on fungal...

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Bibliographische Detailangaben
Hauptverfasser: Brena, Sonia, Cabezas-Olcoz, Jonathan, Moragues, María D., Fernández de Larrinoa, Iñigo, Domínguez, Angel, Quindós, Guillermo, Pontón, José
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3122412/
https://ncbi.nlm.nih.gov/pubmed/21518848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00892-10
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