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The proximal promoter and the start site cooperate to specify correct U1 snRNA transcription initiation by RNA polymerase II.
In this work, we attempted to gain insight into the detailed mechanism allowing correct transcription initiation of U1 snRNA genes by RNA polymerase II. Abolition of the CA motif residing at -1/+1 in the Xenopus U1 gene leads to a loss of the ability of the promoter to direct accurate initiation. A...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
1992
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| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC312240/ https://ncbi.nlm.nih.gov/pubmed/1579449 |
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