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Development, Evaluation, and Application of an In Silico Model for Antimalarial Drug Treatment and Failure

Pharmacological mechanism-based modeling was refined and used to develop an in silico model of antimalarial drug treatment validated against clinical and field data. We used this approach to investigate key features of antimalarial drug action and effectiveness, with emphasis on the current generati...

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Detalhes bibliográficos
Main Authors: Winter, Katherine, Hastings, Ian M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3122393/
https://ncbi.nlm.nih.gov/pubmed/21537019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01712-10
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