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A Forward Genetic Screen Identifies Mutants Deficient for Mitochondrial Complex I Assembly in Chlamydomonas reinhardtii

Mitochondrial complex I is the largest multimeric enzyme of the respiratory chain. The lack of a model system with facile genetics has limited the molecular dissection of complex I assembly. Using Chlamydomonas reinhardtii as an experimental system to screen for complex I defects, we isolated, via f...

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Autors principals: Barbieri, M. Rosario, Larosa, Véronique, Nouet, Cécile, Subrahmanian, Nitya, Remacle, Claire, Hamel, Patrice P.
Format: Artigo
Idioma:Inglês
Publicat: Genetics Society of America 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3122308/
https://ncbi.nlm.nih.gov/pubmed/21467570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.111.128827
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