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Cloning and characterization of chromosome breakpoints of Plasmodium falciparum: breakage and new telomere formation occurs frequently and randomly in subtelomeric genes.

We analysed the genetic stability of two subtelomeric genes of the human malaria parasite Plasmodium falciparum. A PCR based assay, using a telomere and a target-gene specific primer was used to detect potential chromosome rearrangements. We show that chromosome breakage and the formation of new tel...

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Détails bibliographiques
Auteurs principaux: Scherf, A, Mattei, D
Format: Artigo
Langue:Inglês
Publié: 1992
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC312228/
https://ncbi.nlm.nih.gov/pubmed/1579440
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