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Functional Heterogeneity of Osteopontin Isoforms in Non-Small Cell Lung Cancer

INTRODUCTION: Osteopontin (OPN) is a multifunctional protein with an important but poorly understood role in non-small cell lung cancer (NSCLC) pathogenesis. Moreover, the role of the three known mRNA isoforms (OPNa, OPNb, and OPNc) has not been reported. We hypothesize that OPN isoforms play differ...

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Detalhes bibliográficos
Main Authors: Goparaju, C.M.V., Pass, H.I., Blasberg, J.D., Hirsch, N., Donington, J.S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3122268/
https://ncbi.nlm.nih.gov/pubmed/20689445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/JTO.0b013e3181eba6bd
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