Elevated Inflammatory Response in Caveolin-1-deficient Mice with Pseudomonas aeruginosa Infection Is Mediated by STAT3 Protein and Nuclear Factor κB (NF-κB)

Caveolin-1 (Cav-1), an important composition protein within the flask-shaped membrane invaginations termed caveolae, may play a role in host defense against infections. However, the phenotype in Pseudomonas aeruginosa-infected cav1 knock-out (KO) mice is still unresolved, and the mechanism involved...

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Detalhes bibliográficos
Main Authors: Yuan, Kefei, Huang, Canhua, Fox, John, Gaid, Madeleine, Weaver, Andrew, Li, Guoping, Singh, Brij B., Gao, Hongwei, Wu, Min
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3122236/
https://ncbi.nlm.nih.gov/pubmed/21515682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.237628
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