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Converging Evidence of Mitochondrial Dysfunction in a Yeast Model of Homocysteine Metabolism Imbalance

An elevated level of homocysteine, a thiol amino acid, is associated with various complex disorders. The cellular effects of homocysteine and its precursors S-adenosylhomocysteine (AdoHcy) and S-adenosylmethionine (AdoMet) are, however, poorly understood. We used Saccharomyces cerevisiae as a model...

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Detalhes bibliográficos
Main Authors: Kumar, Arun, John, Lijo, Maity, Shuvadeep, Manchanda, Mini, Sharma, Abhay, Saini, Neeru, Chakraborty, Kausik, Sengupta, Shantanu
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3122233/
https://ncbi.nlm.nih.gov/pubmed/21504896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.228072
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