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A Novel GDP-d-glucose Phosphorylase Involved in Quality Control of the Nucleoside Diphosphate Sugar Pool in Caenorhabditis elegans and Mammals

The plant VTC2 gene encodes GDP-l-galactose phosphorylase, a rate-limiting enzyme in plant vitamin C biosynthesis. Genes encoding apparent orthologs of VTC2 exist in both mammals, which produce vitamin C by a distinct metabolic pathway, and in the nematode worm Caenorhabditis elegans where vitamin C...

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Detalhes bibliográficos
Main Authors: Adler, Lital N., Gomez, Tara A., Clarke, Steven G., Linster, Carole L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3122210/
https://ncbi.nlm.nih.gov/pubmed/21507950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.238774
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