SET Nuclear Oncogene Associates with Microcephalin/MCPH1 and Regulates Chromosome Condensation

Primary microcephaly is an autosomal recessive disorder characterized by marked reduction in human brain size. Microcephalin (MCPH1), one of the genes mutated in primary microcephaly, plays an important role in DNA damage checkpoint control and mitotic entry. Additionally, MCPH1 ensures the proper t...

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Bibliographische Detailangaben
Hauptverfasser: Leung, Justin W., Leitch, Andrea, Wood, Jamie L., Shaw-Smith, Charles, Metcalfe, Kay, Bicknell, Louise S., Jackson, Andrew P., Chen, Junjie
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2011
Schlagworte:
DNA and Chromosomes
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3122199/
https://ncbi.nlm.nih.gov/pubmed/21515671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.208793
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