Loss of Xenopus tropicalis EMSY causes impairment of gastrulation and upregulation of p53

EMSY interacts directly with BRCA2 and links the BRCA2 pathway to sporadic breast and ovarian cancer. It also interacts with BS69 and HP1b, both of which are involved in chromatin remodelling, and with NIF-1 and DBC-1 in the regulation of nuclear receptor-mediated transcription. Here we investigate...

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Main Authors: Rana, Amer A., Roper, Stephen J., Palmer, Elizabeth A., Smith, James C.
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2011
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3122151/
https://ncbi.nlm.nih.gov/pubmed/21056705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbt.2010.10.010
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