The propeptide of yeast cathepsin D inhibits programmed necrosis

The lysosomal endoprotease cathepsin D (CatD) is an essential player in general protein turnover and specific peptide processing. CatD-deficiency is associated with neurodegenerative diseases, whereas elevated CatD levels correlate with tumor malignancy and cancer cell survival. Here, we show that t...

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Bibliographic Details
Main Authors: Carmona-Gutiérrez, D, Bauer, M A, Ring, J, Knauer, H, Eisenberg, T, Büttner, S, Ruckenstuhl, C, Reisenbichler, A, Magnes, C, Rechberger, G N, Birner-Gruenberger, R, Jungwirth, H, Fröhlich, K-U, Sinner, F, Kroemer, G, Madeo, F
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2011
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3122122/
https://ncbi.nlm.nih.gov/pubmed/21593793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2011.43
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