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The clinical efficacy of -DOPA and STN-DBS share a common marker: reduced GABA content in the motor thalamus

At odd with traditional views, effective sub-thalamic nucleus (STN) deep brain stimulation (DBS), in Parkinson's disease (PD) patients, may increase the discharge rate of the substantia nigra pars reticulata and the internal globus pallidus (GPi), in combination with increased cyclic guanosine...

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Detalhes bibliográficos
Main Authors: Stefani, A, Fedele, E, Vitek, J, Pierantozzi, M, Galati, S, Marzetti, F, Peppe, A, Bassi, M S, Bernardi, G, Stanzione, P
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3122115/
https://ncbi.nlm.nih.gov/pubmed/21544093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2011.35
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