Calpain-mediated cleavage of Beclin-1 and autophagy deregulation following retinal ischemic injury in vivo

Autophagy is the major intracellular degradation pathway that regulates long-lived proteins and organelles turnover. This process occurs at basal levels in all cells but it is rapidly upregulated in response to starvation and cellular stress. Although being recently implicated in neurodegeneration,...

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Detalhes bibliográficos
Main Authors: Russo, R, Berliocchi, L, Adornetto, A, Varano, G P, Cavaliere, F, Nucci, C, Rotiroti, D, Morrone, L A, Bagetta, G, Corasaniti, M T
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3122060/
https://ncbi.nlm.nih.gov/pubmed/21490676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2011.29
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