Metabolic stress promotes renal tubular inflammation by triggering the unfolded protein response

The renal epithelium contributes to the development of inflammation during ischemic injury. Ischemia induces endoplasmic reticulum (ER) stress and activates the unfolded protein response (UPR). Ischemic tissues generate distress signals and inflammation that activates fibrogenesis and may promote ad...

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Bibliografiske detaljer
Main Authors: Fougeray, S, Bouvier, N, Beaune, P, Legendre, C, Anglicheau, D, Thervet, E, Pallet, N
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2011
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3122058/
https://ncbi.nlm.nih.gov/pubmed/21490675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2011.26
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