Adapting the γ-H2AX Assay for Automated Processing in Human Lymphocytes. 1. Technological Aspects

The immunofluorescence-based detection of γ-H2AX is a reliable and sensitive method for quantitatively measuring DNA double-strand breaks (DSBs) in irradiated samples. Since H2AX phosphorylation is highly linear with radiation dose, this well-established biomarker is in current use in radiation biod...

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Autori principali: Turner, Helen C., Brenner, David J., Chen, Youhua, Bertucci, Antonella, Zhang, Jian, Wang, Hongliang, Lyulko, Oleksandra V., Xu, Yanping, Shuryak, Igor, Schaefer, Julia, Simaan, Nabil, Randers-Pehrson, Gerhard, Yao, Y. Lawrence, Amundson, Sally A., Garty, Guy
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3121903/
https://ncbi.nlm.nih.gov/pubmed/21388271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1667/RR2125.1
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