Structure-based approach to rationally design a chimeric protein for an effective vaccine against Group B Streptococcus infections

Structural vaccinology is an emerging strategy for the rational design of vaccine candidates. We successfully applied structural vaccinology to design a fully synthetic protein with multivalent protection activity. In Group B Streptococcus, cell-surface pili have aroused great interest because of th...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Nuccitelli, Annalisa, Cozzi, Roberta, Gourlay, Louise J., Donnarumma, Danilo, Necchi, Francesca, Norais, Nathalie, Telford, John L., Rappuoli, Rino, Bolognesi, Martino, Maione, Domenico, Grandi, Guido, Rinaudo, C. Daniela
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2011
Gaiak:
Biological Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3121859/
https://ncbi.nlm.nih.gov/pubmed/21593422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1106590108
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