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Discovery of an unusual biosynthetic origin for circular proteins in legumes

Cyclotides are plant-derived proteins that have a unique cyclic cystine knot topology and are remarkably stable. Their natural function is host defense, but they have a diverse range of pharmaceutically important activities, including uterotonic activity and anti-HIV activity, and have also attracte...

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Detalhes bibliográficos
Main Authors: Poth, Aaron G., Colgrave, Michelle L., Lyons, Russell E., Daly, Norelle L., Craik, David J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3121837/
https://ncbi.nlm.nih.gov/pubmed/21593408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1103660108
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