Renal phenotype in mice lacking the Kir5.1 (Kcnj16) K(+) channel subunit contrasts with that observed in SeSAME/EAST syndrome

The heteromeric inwardly rectifying Kir4.1/Kir5.1 K(+) channel underlies the basolateral K(+) conductance in the distal nephron and is extremely sensitive to inhibition by intracellular pH. The functional importance of Kir4.1/Kir5.1 in renal ion transport has recently been highlighted by mutations i...

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Détails bibliographiques
Auteurs principaux: Paulais, Marc, Bloch-Faure, May, Picard, Nicolas, Jacques, Thibaut, Ramakrishnan, Suresh Krishna, Keck, Mathilde, Sohet, Fabien, Eladari, Dominique, Houillier, Pascal, Lourdel, Stéphane, Teulon, Jacques, Tucker, Stephen J.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2011
Sujets:
Biological Sciences
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3121827/
https://ncbi.nlm.nih.gov/pubmed/21633011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1101400108
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