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Pharmacological Characterization of [(3)H]CHIBA-3007 Binding to Glycine Transporter 1 in the Rat Brain

Glycine transporter-1 (GlyT-1) in glial cells regulates extracellular levels of glycine, which acts as an obligatory co-agonist at the N-methyl-D-aspartate (NMDA) receptors in the brain. In the present study, we developed a novel radioligand, [(3)H]3-chloro-N-((S)-((R)-1-methylpiperidin-2-yl)(thioph...

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Autors principals: Zhang, Jichun, Wu, Jin, Toyohara, Jun, Fujita, Yuko, Chen, Hongxian, Hashimoto, Kenji
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3121759/
https://ncbi.nlm.nih.gov/pubmed/21731704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0021322
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