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Redundant Mechanisms Prevent Mitotic Entry Following Replication Arrest in the Absence of Cdc25 Hyper-Phosphorylation in Fission Yeast
Following replication arrest the Cdc25 phosphatase is phosphorylated and inhibited by Cds1. It has previously been reported that expressing Cdc25 where 9 putative amino-terminal Cds1 phosphorylation sites have been substituted to alanine results in bypass of the DNA replication checkpoint. However,...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2011
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3121752/ https://ncbi.nlm.nih.gov/pubmed/21731711 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0021348 |
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