Molecular cytogenetic characterization of canine histiocytic sarcoma: A spontaneous model for human histiocytic cancer identifies deletion of tumor suppressor genes and highlights influence of genetic background on tumor behavior

BACKGROUND: Histiocytic malignancies in both humans and dogs are rare and poorly understood. While canine histiocytic sarcoma (HS) is uncommon in the general domestic dog population, there is a strikingly high incidence in a subset of breeds, suggesting heritable predisposition. Molecular cytogeneti...

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Autori principali: Hedan, Benoit, Thomas, Rachael, Motsinger-Reif, Alison, Abadie, Jerome, Andre, Catherine, Cullen, John, Breen, Matthew
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2011
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3121728/
https://ncbi.nlm.nih.gov/pubmed/21615919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-11-201
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