Inverse baseline expression pattern of the NEP/neuropeptides and NFκB/proteasome pathways in androgen-dependent and androgen-independent prostate cancer cells

BACKGROUND: Castration-resistance in prostate cancer (PC) is a critical event hallmarking a switch to a more aggressive phenotype. Neuroendocrine differentiation and upregulation of NFκB transcriptional activity are two mechanisms that have been independently linked to this process. METHODS: We inve...

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Autors principals: Patrikidou, Anna, Vlachostergios, Panagiotis J, Voutsadakis, Ioannis A, Hatzidaki, Eleana, Valeri, Rosalia-Maria, Destouni, Chariklia, Apostolou, Effie, Daliani, Danai, Papandreou, Christos N
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2011
Matèries:
Primary Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3121665/
https://ncbi.nlm.nih.gov/pubmed/21569620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2867-11-13
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