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Homer1a signaling in the amygdala counteracts pain-related synaptic plasticity, mGluR1 function and pain behaviors

BACKGROUND: Group I metabotropic glutamate receptor (mGluR1/5) signaling is an important mechanism of pain-related plasticity in the amygdala that plays a key role in the emotional-affective dimension of pain. Homer1a, the short form of the Homer1 family of scaffolding proteins, disrupts the mGluR-s...

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Détails bibliographiques
Auteurs principaux: Tappe-Theodor, Anke, Fu, Yu, Kuner, Rohini, Neugebauer, Volker
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3121594/
https://ncbi.nlm.nih.gov/pubmed/21595930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-8069-7-38
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