Metabolic Remodeling of Human Skeletal Myocytes by Cocultured Adipocytes Depends on the Lipolytic State of the System

OBJECTIVE: Adipocyte infiltration of the musculoskeletal system is well recognized as a hallmark of aging, obesity, and type 2 diabetes. Intermuscular adipocytes might serve as a benign storage site for surplus lipid or play a role in disrupting energy homeostasis as a result of dysregulated lipolys...

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Autori principali: Kovalik, Jean-Paul, Slentz, Dorothy, Stevens, Robert D., Kraus, William E., Houmard, Joseph A., Nicoll, James B., Lea-Currie, Y. Renee, Everingham, Karen, Kien, C. Lawrence, Buehrer, Benjamin M., Muoio, Deborah M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Diabetes Association 2011
Soggetti:
Metabolism
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3121442/
https://ncbi.nlm.nih.gov/pubmed/21602515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db10-0427
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