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Switch I Closure Simultaneously Promotes Strong Binding to Actin and ADP in Smooth Muscle Myosin

The motor protein myosin uses energy derived from ATP hydrolysis to produce force and motion. Important conserved components (P-loop, switch I, and switch II) help propagate small conformational changes at the active site into large scale conformational changes in distal regions of the protein. Stru...

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Detalhes bibliográficos
Main Authors: Decarreau, Justin A., James, Nicholas G., Chrin, Lynn R., Berger, Christopher L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3121376/
https://ncbi.nlm.nih.gov/pubmed/21536675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.219014
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