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Switch I Closure Simultaneously Promotes Strong Binding to Actin and ADP in Smooth Muscle Myosin
The motor protein myosin uses energy derived from ATP hydrolysis to produce force and motion. Important conserved components (P-loop, switch I, and switch II) help propagate small conformational changes at the active site into large scale conformational changes in distal regions of the protein. Stru...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Biochemistry and Molecular Biology
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3121376/ https://ncbi.nlm.nih.gov/pubmed/21536675 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.219014 |
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