Topiramate diminishes fear memory consolidation and extinguishes conditioned fear in rats

BACKGROUND: Topiramate has been recognized as a drug that can induce memory and cognitive impairment. Using the one-trial inhibitory avoidance task, we sought to verify the effect of topiramate on consolidation and extinction of aversive memory. Our hypothesis was that topiramate inhibits the consol...

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Detalles Bibliográficos
Autores principales: do Prado-Lima, Pedro Antônio Schmidt, Perrenoud, Myriam Fortes, Kristensen, Christian Haag, Cammarota, Martin, Izquierdo, Ivan
Formato: Artigo
Lenguaje:Inglês
Publicado: Canadian Medical Association 2011
Materias:
Research Papers
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3120893/
https://ncbi.nlm.nih.gov/pubmed/21392483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1503/jpn.100115
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