An Information Theoretic, Microfluidic-Based Single Cell Analysis Permits Identification of Subpopulations among Putatively Homogeneous Stem Cells

An incomplete understanding of the nature of heterogeneity within stem cell populations remains a major impediment to the development of clinically effective cell-based therapies. Transcriptional events within a single cell are inherently stochastic and can produce tremendous variability, even among...

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Detalhes bibliográficos
Main Authors: Glotzbach, Jason P., Januszyk, Michael, Vial, Ivan N., Wong, Victor W., Gelbard, Alexander, Kalisky, Tomer, Thangarajah, Hariharan, Longaker, Michael T., Quake, Stephen R., Chu, Gilbert, Gurtner, Geoffrey C.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3120839/
https://ncbi.nlm.nih.gov/pubmed/21731674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0021211
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