HMGB1 Attenuates Cardiac Remodelling in the Failing Heart via Enhanced Cardiac Regeneration and miR-206-Mediated Inhibition of TIMP-3

AIMS: HMGB1 injection into the mouse heart, acutely after myocardial infarction (MI), improves left ventricular (LV) function and prevents remodeling. Here, we examined the effect of HMGB1 in chronically failing hearts. METHODS AND RESULTS: Adult C57 BL16 female mice underwent coronary artery ligati...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Hoofdauteurs: Limana, Federica, Esposito, Grazia, D'Arcangelo, Daniela, Di Carlo, Anna, Romani, Sveva, Melillo, Guido, Mangoni, Antonella, Bertolami, Chiara, Pompilio, Giulio, Germani, Antonia, Capogrossi, Maurizio C.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2011
Onderwerpen:
Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3120764/
https://ncbi.nlm.nih.gov/pubmed/21731608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0019845
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items