HMGB1 Attenuates Cardiac Remodelling in the Failing Heart via Enhanced Cardiac Regeneration and miR-206-Mediated Inhibition of TIMP-3

AIMS: HMGB1 injection into the mouse heart, acutely after myocardial infarction (MI), improves left ventricular (LV) function and prevents remodeling. Here, we examined the effect of HMGB1 in chronically failing hearts. METHODS AND RESULTS: Adult C57 BL16 female mice underwent coronary artery ligati...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Limana, Federica, Esposito, Grazia, D'Arcangelo, Daniela, Di Carlo, Anna, Romani, Sveva, Melillo, Guido, Mangoni, Antonella, Bertolami, Chiara, Pompilio, Giulio, Germani, Antonia, Capogrossi, Maurizio C.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2011
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3120764/
https://ncbi.nlm.nih.gov/pubmed/21731608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0019845
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