Simvastatin Prevents Dopaminergic Neurodegeneration in Experimental Parkinsonian Models: The Association with Anti-Inflammatory Responses

BACKGROUND: In addition to their original applications to lowering cholesterol, statins display multiple neuroprotective effects. N-methyl-D-aspartate (NMDA) receptors interact closely with the dopaminergic system and are strongly implicated in therapeutic paradigms of Parkinson's disease (PD)....

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Main Authors: Yan, Junqiang, Xu, Yunqi, Zhu, Cansheng, Zhang, Limin, Wu, Aimin, Yang, Yu, Xiong, Zhaojun, Deng, Chao, Huang, Xu-Feng, Yenari, Midori A., Yang, Yuan-Guo, Ying, Weihai, Wang, Qing
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2011
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3120752/
https://ncbi.nlm.nih.gov/pubmed/21731633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0020945
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