Expression of constitutively active erythropoietin receptor in pyramidal neurons of cortex and hippocampus boosts higher cognitive functions in mice

BACKGROUND: Erythropoietin (EPO) and its receptor (EPOR) are expressed in the developing brain and their transcription is upregulated in adult neurons and glia upon injury or neurodegeneration. We have shown neuroprotective effects and improved cognition in patients with neuropsychiatric diseases tr...

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Detalhes bibliográficos
Main Authors: Sargin, Derya, El-Kordi, Ahmed, Agarwal, Amit, Müller, Michael, Wojcik, Sonja M, Hassouna, Imam, Sperling, Swetlana, Nave, Klaus-Armin, Ehrenreich, Hannelore
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3120735/
https://ncbi.nlm.nih.gov/pubmed/21527022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1741-7007-9-27
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