Expression of constitutively active erythropoietin receptor in pyramidal neurons of cortex and hippocampus boosts higher cognitive functions in mice

BACKGROUND: Erythropoietin (EPO) and its receptor (EPOR) are expressed in the developing brain and their transcription is upregulated in adult neurons and glia upon injury or neurodegeneration. We have shown neuroprotective effects and improved cognition in patients with neuropsychiatric diseases tr...

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Autori principali: Sargin, Derya, El-Kordi, Ahmed, Agarwal, Amit, Müller, Michael, Wojcik, Sonja M, Hassouna, Imam, Sperling, Swetlana, Nave, Klaus-Armin, Ehrenreich, Hannelore
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2011
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3120735/
https://ncbi.nlm.nih.gov/pubmed/21527022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1741-7007-9-27
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