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Discrimination of approved drugs from experimental drugs by learning methods

BACKGROUND: To assess whether a compound is druglike or not as early as possible is always critical in drug discovery process. There have been many efforts made to create sets of 'rules' or 'filters' which, it is hoped, will help chemists to identify 'drug-like' molecul...

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Autores principales: Tang, Kailin, Zhu, Ruixin, Li, Yixue, Cao, Zhiwei
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3120701/
https://ncbi.nlm.nih.gov/pubmed/21569562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-12-157
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