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AMP-activated protein kinase deficiency reduces ozone-induced lung injury and oxidative stress in mice

BACKGROUND: Acute ozone exposure causes lung oxidative stress and inflammation leading to lung injury. At least one mechanism underlying the lung toxicity of ozone involves excessive production of reactive oxygen and nitrogen intermediates such as peroxynitrite. In addition and beyond its major proo...

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Bibliografische gegevens
Hoofdauteurs: Hulo, Sébastien, Tiesset, Hélène, Lancel, Steve, Viollet, Benoit, Sobaszek, Annie, Nevière, Rémi
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2011
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3120668/
https://ncbi.nlm.nih.gov/pubmed/21595935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-12-64
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