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Upstream regions of the c-jun promoter regulate phorbol ester-induced transcription in U937 leukemic cells.

To understand the mechanism by which phorbol esters (PMA) stimulate c-jun transcription in human leukemic cell line U937, we have mutated specific enhancer sequences within the c-jun promoter. We find in the region of DNA from -132 to +170 containing Sp1, C-TF and AP-1 sequences that mutation of the...

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Autori principali: Unlap, T, Franklin, C C, Wagner, F, Kraft, A S
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1992
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC312034/
https://ncbi.nlm.nih.gov/pubmed/1542579
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