Screening for mutations by RNA single-strand conformation polymorphism (rSSCP): comparison with DNA-SSCP.
Single-strand conformation polymorphism (SSCP) is a simple method for detecting the presence of mutations in a segment of DNA, but the fraction of all mutations detected is unclear. We have evaluated SSCP for the detection of single-base mutations in the factor IX gene. Multiple conditions were exam...
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| Pubblicato in: | Nucleic Acids Res |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
1992
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| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC312031/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1371869/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/20.4.871 |
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