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Treatment of Cultured Sebocytes with an EGFR Inhibitor Does Not Lead to Significant Upregulation of Inflammatory Biomarkers

BACKGROUND: Epidermal growth factor receptor (EGFR) inhibitors are being used to treat malignancies originating from epithelia. Unfortunately, blocking the EGFR pathway leads to various side effects, most frequently acneiform eruptions. OBJECTIVE: To probe the mechanism underlying this side effect,...

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Detalhes bibliográficos
Main Authors: Lee, Weon Ju, Chi, Seong Geun, Park, Dong Jae, Kim, Jun Young, Kim, Ho Youn, Lee, Seok-Jong, Kim, Do Won, Kim, Moon Kyu, Kim, Jung Chul, Lee, Mi Woo
Formato: Artigo
Idioma:Inglês
Publicado em: Korean Dermatological Association; The Korean Society for Investigative Dermatology 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3119992/
https://ncbi.nlm.nih.gov/pubmed/21738357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5021/ad.2011.23.1.12
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