Nicotinamide Adenine Dinucleotide Phosphate Reduced Oxidase 5 (Nox5) Regulation by Angiotensin II and Endothelin-1 is Mediated via Calcium/Calmodulin-dependent, Rac-1-independent Pathways in Human Endothelial Cells

RATIONALE: Although Nox5, (Nox2 homologue), has been identified in the vasculature, its regulation and functional significance remain unclear. OBJECTIVES: To test if vasoactive agents regulate Nox5 through Ca(2+)/calmodulin-dependent processes and whether Ca(2+) -sensitive Nox5, associated with Rac-...

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Detalhes bibliográficos
Main Authors: Montezano, Augusto C, Burger, Dylan, Paravicini, Tamara M, Chignalia, Andreia Z, Yusuf, Hiba, Almasri, Mahmoud, He, Ying, Callera, Glaucia E, He, Gang, Krause, Karl-Heinz, Lambeth, David, Quinn, Mark T, Touyz, Rhian M
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3119893/
https://ncbi.nlm.nih.gov/pubmed/20339118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.109.216036
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