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Serum Amyloid A (SAA) Activates the NLRP3 Inflammasome and Promotes T(H)17 Allergic Asthma in Mice
Interleukin (IL)-1β is a cytokine critical to several inflammatory diseases in which pathogenic T(H)17 responses are implicated. Activation of the NLRP3 inflammasome by microbial and environmental stimuli can enable the caspase-1 dependent processing and secretion of IL-1β. The acute phase protein s...
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Main Authors: | , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3119761/ https://ncbi.nlm.nih.gov/pubmed/21622869 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1100500 |
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