MHC class II epitope nesting modulates dendritic cell function and improves generation of antigen-specific CD4 helper T cells

CD4 T helper cells are critical to the development of coordinated immune responses to infections and tumors. T helper cells are activated through interactions of the TCR with MHC class II complexed with peptide. T cell activation is dependent on the density of MHC peptide complexes as well as the du...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Erskine, Courtney L., Krco, Christopher J., Hedin, Karen E., Borson, Nancy D., Kalli, Kimberly R., Behrens, Marshall D., Heman-Ackah, Sabrina M., von Hofe, Eric, Wettstein, Peter J., Mohamadzadeh, Mansour, Knutson, Keith L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3119756/
https://ncbi.nlm.nih.gov/pubmed/21613617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1100658
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi