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MHC class II epitope nesting modulates dendritic cell function and improves generation of antigen-specific CD4 helper T cells
CD4 T helper cells are critical to the development of coordinated immune responses to infections and tumors. T helper cells are activated through interactions of the TCR with MHC class II complexed with peptide. T cell activation is dependent on the density of MHC peptide complexes as well as the du...
Kaydedildi:
Asıl Yazarlar: | , , , , , , , , , , |
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Materyal Türü: | Artigo |
Dil: | Inglês |
Baskı/Yayın Bilgisi: |
2011
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Konular: | |
Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3119756/ https://ncbi.nlm.nih.gov/pubmed/21613617 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1100658 |
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