Tuning Core vs. Shell Dimensions to Adjust the Performance of Nanoscopic Containers for the Loading and Release of Doxorubicin

Detailed studies were performed to probe the effects of the core and shell dimensions of amphiphilic, shell crosslinked, knedel-like polymer nanoparticles (SCKs) on the loading and release of doxorubicin (DOX), a widely-used chemotherapy agent, in aqueous buffer, as a function of the solution pH. Ef...

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Détails bibliographiques
Auteurs principaux: Lin, Lily Yun, Lee, Nam S., Zhu, Jiahua, Nyström, Andreas M., Pochan, Darrin J., Dorshow, Richard B., Wooley, Karen L.
Format: Artigo
Langue:Inglês
Publié: 2011
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3119510/
https://ncbi.nlm.nih.gov/pubmed/21241750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2011.01.009
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