NOD Dendritic Cells Stimulated with Lactobacilli Preferentially Produce IL-10 versus IL-12 and Decrease Diabetes Incidence

Dendritic cells (DCs) from NOD mice produced high levels of IL-12 that induce IFNγ-producing T cells involved in diabetes development. We propose to utilize the microorganism ability to induce tolerogenic DCs to abrogate the proinflammatory process and prevent diabetes development. NOD DCs were stim...

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Bibliographic Details
Main Authors: Manirarora, Jean N., Parnell, Sarah A., Hu, Yoon-Hyeon, Kosiewicz, Michele M., Alard, Pascale
Format: Artigo
Language:Inglês
Published: Hindawi Publishing Corporation 2011
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3119457/
https://ncbi.nlm.nih.gov/pubmed/21716731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2011/630187
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