Tissue‐specific regulatory regions of the PTH gene localized by novel chromosome 11 rearrangement breakpoints in a parathyroid adenoma

Parathyroid adenomas can contain clonal rearrangements of chromosome 11 that activate the cyclin D1 oncogene through juxtaposition with the PTH gene. Here we describe such a chromosomal rearrangement whose novel features provide clues to locating elusive cis‐regulatory elements in the PTH gene and a...

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Bibliografiska uppgifter
Huvudupphovsmän: Mallya, Sanjay M, Wu, H Irene, Saria, Elizabeth A, Corrado, Kristin R, Arnold, Andrew
Materialtyp: Artigo
Språk:Inglês
Publicerad: Wiley Subscription Services, Inc., A Wiley Company 2010
Ämnen:
Original Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3119366/
https://ncbi.nlm.nih.gov/pubmed/20641034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.187
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