High susceptibility of c-KIT(+)CD34(+) precursors to prolonged doxorubicin exposure interferes with Langerhans cell differentiation in a human cell line model

As neoadjuvant and adjuvant chemotherapy schedules often consist of multiple treatment cycles over relatively long periods of time, it is important to know what effects protracted drug administration can have on the immune system. Here, we studied the long-term effects of doxorubicin on the capacity...

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Autores principales: van de Ven, Rieneke, Verbrugge, Sue Ellen, Reurs, Anneke W., Bontkes, Hetty J., Hooijberg, Erik, Jansen, Gerrit, Scheper, Rik J., Scheffer, George L., de Gruijl, Tanja D.
Formato: Artigo
Lenguaje:Inglês
Publicado: Springer-Verlag 2011
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3119330/
https://ncbi.nlm.nih.gov/pubmed/21431918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-011-1003-9
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