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Disruption of the Transient Receptor Potential Vanilloid Subtype-1 Can Affect Survival, Bacterial Clearance, and Cytokine Gene Expression during Murine Sepsis

BACKGROUND: Previous studies suggest that the transient receptor potential vanilloid-1 (TRPV1) has a role in sepsis but it is unclear whether its effect on survival and immune response is beneficial or harmful. METHODS: We studied the effects of genetic (Trpv1-knock out vs. wild-type mice) and pharm...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Guptill, Virginia, Cui, Xizhong, Khaibullina, Alfia, Keller, Jason M., Spornick, Nicholas, Mannes, Andrew, Iadarola, Michael, Quezado, Zenaide M.N.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3119195/
https://ncbi.nlm.nih.gov/pubmed/21383614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0b013e318212515b
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