Upregulation of P-glycoprotein by probiotics in intestinal epithelial cells and in the dextran sulfate sodium model of colitis in mice

P-glycoprotein (P-gp) mediates efflux of xenobiotics and bacterial toxins from the intestinal mucosa into the lumen. Dysregulation of P-gp has been implicated in inflammatory bowel disease. Certain probiotics have been shown to be effective in treating inflammatory bowel disease. However, direct eff...

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Autori principali: Saksena, Seema, Goyal, Sonia, Raheja, Geetu, Singh, Varsha, Akhtar, Maria, Nazir, Talat M., Alrefai, Waddah A., Gill, Ravinder K., Dudeja, Pradeep K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2011
Soggetti:
Mucosal Biology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3119110/
https://ncbi.nlm.nih.gov/pubmed/21350189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00027.2011
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